State	Study Site	Indication	Title	Description	Details
TX	Austin (Balcones, Cancer Center, Round Rock ) Beaumont, Bedford (Harris HEB ) Dallas (Medical City, Presbyterian, Sammons CC ) El Paso (East, West ) Houston (Frostwood ) Plano, Sugar Land, Tyler	Breast Cancer	Phase II Randomized Trial of Neoadjuvant Trastuzumab and/or Lapatinib plus Chemotherapy (Sequential FEC75 and Paclitaxel) in Women with ErbB2- (HER2/neu-) Overexpressing Invasive Breast Cancer	This research study is open to participants who have been diagnosed with breast cancer and “Neoadjuvant” chemotherapy is recommended. This research study is trying to find out if an investigational drug, lapatinib, will improve neoadjuvant breast cancer t	View
NM TX	Abilene (South ) Amarillo, Arlington (North, South ) Austin (Balcones, Cancer Center, Round Rock ) Beaumont, Bedford (Harris HEB ) Dallas (Medical City, Methodist, Presbyterian, Sammons CC ) Denton, El Paso (East, West ) Fort Worth (12th Ave., Southwest ) Garland, Houston (Frostwood ) Las Cruces (Roadrunner ) Lewisville, Longview, McAllen, Mesquite, Midland, Odessa, Paris, PlanoWest ) Sherman, Sugar Land, Tyler, Waco, Webster- Clear Lake ) Weslaco, Wichita Falls	Breast Cancer	Phase III Trial of Adjuvant TC versus TAC in HER2-Negative Early Stage Breast Cancer Patients	This research study is open to women who have been diagnosed as having early stage HER2-negative (–) breast cancer. Taxotere, Adriamycin, and Cytoxan in combination are FDA-approved for the treatment of early stage breast cancer. TC has also been used	View
TX	Abilene (South ) Arlington (North, South ) Austin (Balcones, Cancer Center, Round Rock ) Beaumont, Bedford (Harris HEB ) Dallas (Medical City, Methodist, Presbyterian, Sammons CC ) El Paso (East, West ) Fort Worth (12th Ave., Southwest ) Garland, Houston (Frostwood ) Lewisville, Longview, McAllen, Mesquite, Midland, Odessa, Paris, Plano, Sherman, Sugar Land, Tyler, Waco, Webster- Clear Lake ) Weslaco, Wichita Falls	Breast Cancer	Pilot Study of Femara Following 1-5 Years of Tamoxifen in Women in Their 40s with Early Stage or Locally Advanced Breast Cancer Who Have Ceased Menstruating with Adjuvant Chemotherapy	This research study is open to women in their 40s who: · Were having periods (premenopausal) at the time of diagnosis with early stage or locally advanced breast cancer or was not known to be in menopause if they had undergone a hysterectomy · Are no	View
TX	Austin (Balcones, Cancer Center ) Dallas (Presbyterian, Sammons CC ) El Paso (East, West ) Fort Worth (12th Ave. ) Waco	Fallopian Tube Cancer	A Phase II, Multicenter, Randomized, Blinded, Placebo-Controlled Trial of Carboplatin and Gemcitabine Plus Bevacizumab in Patients with Platinum-Sensitive Recurrent Ovary, Primary Peritoneal, or Fallopian Tube Carcinoma	This research study is open to qualified individuals who have been diagnosed as having cancer of the ovary, peritoneum or fallopian tube. The purpose of this research study is to find out what effects (good and bad) bevacizumab has on cancer of the ova	View
TX	Austin (Balcones, Cancer Center ) Bedford (Harris HEB ) Dallas (Sammons CC ) Waco	Fallopian Tube Cancer	A Randomized, Parallel Group, Open-Label, Active Controlled, Multicenter Phase III Trial of Patupilone (EPO906) versus Pegylated Liposomal Doxorubicin (Doxil/Caelyx) in Taxane/Platinum Refractory/Resistant Patients with Recurrent Epithelial Ovarian, Prima	This research study is open to individuals who have taxane/platinum refractory/resistant, recurrent epithelial ovarian, primary fallopian or primary peritoneal cancer. This means, the ovarian cancer did not respond or recurred less than 6 months after an	View
TX	Dallas (Presbyterian, Sammons CC ) Tyler	Gastric Cancer	A Randomized Phase II Study of Docetaxel in Combination with Oxaliplatin with or without 5-FU or Capecitabine in Metastatic or Locally Recurrent Gastric Cancer previously untreated with Chemotherapy for Advanced Disease	This research study is open to individuals who have been diagnosed as having metastatic or locally recurrent gastric cancer. The purpose of this research study is to determine the efficacy of new combinations of chemotherapy drugs (Taxotere®, Eloxat	View
TX	Amarillo, Arlington (South ) Austin (Balcones, Cancer Center, Round Rock ) Beaumont, Bedford (Harris HEB ) Dallas (Medical City, Methodist, Presbyterian, Sammons CC ) Denton, El Paso (East, West ) Fort Worth (12th Ave., Southwest ) Garland, Lewisville, Longview, Mesquite, Midland, Odessa, Paris, Plano, Tyler, Waco	Gastric Cancer	Phase II trial of docetaxel plus oxaliplatin (DOCOX) with or without cetuximab in patients with metastatic gastric and/or gastroesophageal junction adenocarcinoma	This research study is open to individuals diagnosed with metastatic gastric (stomach) and/or gastroesophageal junction (GEJ) adenocarcinoma. This study is being done to investigate a new combination of drugs (docetaxel, oxaliplatin, and cetuximab). D	View
TX	Abilene (South ) Amarillo, Arlington (South ) Denton, Fort Worth (12th Ave., Southwest ) Lewisville, Longview, McAllen, Midland, Sugar Land, Waco, Webster- Clear Lake ) Weslaco, Wichita Falls	Hematologic	Examination of PNH, by Level Of CD59 on Red and white blood cells, in bone marrow failure syndromes (EXPLORE)	This research study is open to individuals who have been asked to take part in an observational research study, which means that they will not take any study drug. The participants will be asked to provide blood samples for evaluation. The purpose of	View
TX	Bedford (Harris HEB ) Dallas (Medical City, Sammons CC ) Plano	Leukemia	A Randomized, Open-Label, Multicenter, Phase 2 Study to Evaluate the Safety and Efficacy of Lumiliximab in Combination With Fludarabine, Cyclophosphamide, and Rituximab Versus Fludarabine, Cyclophosphamide, and Rituximab Alone in Subjects with Relapsed Ch	This research study is open to participants who have been diagnosed as having Chronic Lymphocytic Leukemia (CLL) and their disease has returned or did not respond to their last treatment. The purpose of this research study is to find out what effects (	View
TX	Amarillo, Austin (Balcones, Cancer Center, Round Rock ) Bedford (Harris HEB ) Dallas (Medical City, Sammons CC, Sammons TOPS ) Fort Worth (12th Ave., Southwest ) Garland, Longview, Midland, PlanoWest ) Tyler	Lung Cancer	A Randomized, Placebo-controlled, Double-blind, Multicenter Phase 2 Study with a Lead in Phase of Erlotinib With or Without SNDX-275 in Patients with Non-small Cell Lung Carcinoma After Failure In Up to Two Prior Chemotherapeutic Regimens for Advanced Dis	This research study is open to individuals who have been diagnosed as having Non-Small Cell Lung Cancer and have failed at least one, but not more than two, chemotherapy regimens and are now being prescribed erlotinib. SNDX-275 is a tablet taken by mou	View
TX	Tyler	Lung Cancer	Open-label phase 1b study of erlotinib plus bevacizumab and IMO-2055 in patients with non-small cell lung cancer who have progressed following initial chemotherapy for advanced or metastatic disease	This research study is open to individuals with non-small cell lung cancer that has worsened following standard treatment. The purpose of this research study is to evaluate the safety of and to determine the highest safe dose of the investigational age	View
TX	Abilene (South ) Arlington (North, South ) Bedford (Harris HEB ) Dallas (Medical City, Presbyterian, Sammons CC ) Mesquite, Plano, Sugar Land, Tyler, Waco	Lung Cancer	Randomized Phase III Study of Docetaxel or Pemetrexed with or without Cetuximab in Patients with Recurrent or Progressive Non-Small Cell Lung Cancer after Platinum-Based Therapy (IMCL CP02-0452)	This research study is open to individuals who have non-small cell lung cancer that cannot be cured with surgery, radiation therapy or chemotherapy and has grown after receiving chemotherapy that included cisplatin or carboplatin (platinum-based therapy).	View
TX	Fort Worth (12th Ave., Southwest ) Tyler	Lymphomas	A Phase II, Multicenter, Open-Label Trial Evaluating The Activity And Tolerability Of Romidepsin (Depsipeptide, FK228) In Progressive or Relapsed Peripheral T-Cell Lymphoma Following Prior Systemic Therapy	This research study is open to individuals with peripheral T-cell lymphoma who have been previously treated for their disease and either the treatment did not work, or their disease has come back. The purpose of this research study is to find out what	View
TX	Abilene (South ) Dallas (Medical City, Sammons CC ) Tyler	Lymphomas	A Phase III, Randomized, Double-Blind Study of Galiximab in Combination with Rituximab Compared with Rituximab in Combination with Placebo for the Treatment of Subjects with Relapsed or Refractory, Follicular Non-Hodgkin's Lymphoma	This research study is open to individuals who have been diagnosed as having Follicular Non-Hodgkin’s Lymphoma (NHL) and their disease has returned or they did not respond to their last treatment. Galiximab is an investigational drug that is being studied	View
TX	Austin (Balcones, Cancer Center, Round Rock ) Dallas (Medical City ) McAllen, Plano, Tyler, Weslaco, Wichita Falls	Lymphomas	PRELUDE: A Phase 3 Clinical Study to Investigate the Prevention of Relapse in Lymphoma Using Daily Enzastaurin	This research study is open to individuals who have been diagnosed with Diffuse Large B-Cell Lymphoma. The purpose of this research study is to find out what effects (good and bad) Enzastaurin has on an individual and their Diffuse Large B-Cell Lymphom	View
TX	Dallas (Medical City, Presbyterian ) Fort Worth (12th Ave., Southwest ) Plano, Tyler, Waco	Myelomas	A Randomized, Blinded, Placebo-Controlled, Multicenter, Phase II Study of Bevacizumab in Combination with Bortezomib in Patients with Relapsed or Refractory Multiple Myeloma	This research study is open to participants’ with relapsed or refractory multiple myeloma. Bevacizumab interferes with a protein (Vascular Endothelial Growth Factor or VEGF) that is important in blood vessel formation. It may prevent growth of blood v	View
TX	Austin (Balcones, Cancer Center ) Dallas (Presbyterian, Sammons CC ) El Paso (East, West ) Fort Worth (12th Ave. ) Waco	Ovarian Cancer	A Phase II, Multicenter, Randomized, Blinded, Placebo-Controlled Trial of Carboplatin and Gemcitabine Plus Bevacizumab in Patients with Platinum-Sensitive Recurrent Ovary, Primary Peritoneal, or Fallopian Tube Carcinoma	This research study is open to qualified individuals who have been diagnosed as having cancer of the ovary, peritoneum or fallopian tube. The purpose of this research study is to find out what effects (good and bad) bevacizumab has on cancer of the ova	View
TX	Austin (Balcones, Cancer Center ) Bedford (Harris HEB ) Dallas (Sammons CC ) Waco	Ovarian Cancer	A Randomized, Parallel Group, Open-Label, Active Controlled, Multicenter Phase III Trial of Patupilone (EPO906) versus Pegylated Liposomal Doxorubicin (Doxil/Caelyx) in Taxane/Platinum Refractory/Resistant Patients with Recurrent Epithelial Ovarian, Prima	This research study is open to individuals who have taxane/platinum refractory/resistant, recurrent epithelial ovarian, primary fallopian or primary peritoneal cancer. This means, the ovarian cancer did not respond or recurred less than 6 months after an	View
TX	Dallas (Methodist, Presbyterian ) Tyler	Pancreatic Cancer	A Phase 2 Double-Blind, Placebo Controlled, Multi-center Adjuvant Trial of the Efficacy, Immunogenicity, and Safety of GI-4000; an Inactivated Recombinant Saccharomyces cerevisiae Expressing Mutant Ras Protein Combined with a Gemcitabine Regimen Versus a	This research study is open to individuals who have pancreatic cancer. The investigational medication in this study is called GI-4000. GI-4000 is a series of three separate products, GI-4014, GI-4015 and GI-4016. An individual’s specific tumor type will	View
TX	Dallas (Sammons TOPS )	Pancreatic Cancer	A randomized phase I/II study with gemcitabine (Gemzar®) and RTA 402 or Gemzar and placebo for patients with unresectable pancreatic cancer	This research study is open to individuals with metastatic pancreatic cancer. The purpose of this research study is to find out what effects (good and bad) RTA 402 plus Gemzar (gemcitabine) (in the Phase I study) or, in Phase II, RTA 402 plus Gemzar (	View
TX	Austin (Balcones, Cancer Center ) Dallas (Presbyterian, Sammons CC ) El Paso (East, West ) Fort Worth (12th Ave. ) Waco	Peritoneal Cancer	A Phase II, Multicenter, Randomized, Blinded, Placebo-Controlled Trial of Carboplatin and Gemcitabine Plus Bevacizumab in Patients with Platinum-Sensitive Recurrent Ovary, Primary Peritoneal, or Fallopian Tube Carcinoma	This research study is open to qualified individuals who have been diagnosed as having cancer of the ovary, peritoneum or fallopian tube. The purpose of this research study is to find out what effects (good and bad) bevacizumab has on cancer of the ova	View
TX	Austin (Balcones, Cancer Center ) Bedford (Harris HEB ) Dallas (Sammons CC ) Waco	Peritoneal Cancer	A Randomized, Parallel Group, Open-Label, Active Controlled, Multicenter Phase III Trial of Patupilone (EPO906) versus Pegylated Liposomal Doxorubicin (Doxil/Caelyx) in Taxane/Platinum Refractory/Resistant Patients with Recurrent Epithelial Ovarian, Prima	This research study is open to individuals who have taxane/platinum refractory/resistant, recurrent epithelial ovarian, primary fallopian or primary peritoneal cancer. This means, the ovarian cancer did not respond or recurred less than 6 months after an	View
TX	Amarillo, Arlington (South ) Austin (Balcones, Cancer Center, Round Rock ) Dallas (Sammons CC ) Midland, Paris, Webster	Prostate Cancer	A Randomized, Double Blind, Placebo Controlled, Multicenter, Phase 2 Study Comparing AT-101 in Combination with Docetaxel and Prednisone versus Docetaxel and Prednisone in Men with Chemotherapy Naïve Metastatic Hormone Refractory Prostate Cancer (HRPC)	This research study is open to individuals with metastatic (cancer that has spread to other parts of your body) hormone refractory prostate cancer and your cancer is progressing (getting worse). Ascenta Therapeutics Inc., the sponsor of this study, has	View
NM TX	Amarillo, Austin (Balcones, Cancer Center, Round Rock ) Beaumont, Dallas (Medical City, Methodist, Sammons CC ) Denton, El Paso (East, West ) Fort Worth (12th Ave., Southwest ) Las Cruces (Roadrunner ) Lewisville, Longview, Midland, Odessa, Paris, Plano, Sherman, Sugar Land, Tyler, Waco, Webster- Clear Lake ) Wichita Falls	Rectal Cancer	A randomized Phase II trial of pre-operative chemoradiotherapy with or without cetuximab (ERBITUX(R)) in locally-advanced adenocarcinoma of the rectum	Participants who have been diagnosed as having rectal cancer may take part in this study. Radiation and 5-fluorouracil (5-FU) have been used together since the late 1960s to reduce the size of rectal tumors, prior to surgery. Cetuximab (Erbitux) is a	View
TX	Dallas (Sammons TOPS ) Tyler	Solid Tumors	A Phase I Open Label, Multicenter, Dose-Escalation Study to Determine the Maximum Tolerated Dose (MTD), Dose Limiting Toxicity (DLT), Safety and Pharmacokinetics of CGC-11047 when Used in Individual Combinations with 1) Gemcitabine or 2) Docetaxel or 3) B	This research study is open to individuals who have been diagnosed as having solid tumors or lymphoma. CGC-11047 is an investigational agent that has been tested in about 20 persons with solid tumors or lymphoma. It is not known how this investigatio	View